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KINASES, MITOGEN-ACTIVATED PROTEIN
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DeCS
Descriptor
English
:
Mitogen-Activated Protein Kinases
Descriptor
Spanish
:
Proteínas Quinasas Activadas por Mitógenos
Descriptor
Portuguese
:
Proteínas Quinases Ativadas por Mitógeno
Synonyms
English
:
Kinases, Mitogen-Activated Protein
Mitogen Activated Protein Kinases
Protein Kinases, Mitogen-Activated
Tree Number:
D08.811.913.696.620.682.700.567
D12.644.360.450
D12.776.476.450
Definition
English
:
A superfamily of
PROTEIN-SERINE-THREONINE KINASES
that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by
phosphorylation
by
MITOGEN-ACTIVATED PROTEIN KINASE KINASES
, which in turn are activated by mitogen-activated protein kinase kinase kinases (
MAP KINASE KINASE KINASES
).
See Related
English
:
MAP Kinase Signaling System
History Note
English
:
2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES use CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34450
Unique Identifier:
D020928
Occurrence in VHL
:
Similar:
DeCS